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BIO C111 General
Biology
3 0 3
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Living
systems and their properties; major biological compounds;
basic physiological processes; introduction to genetics;
environment and evolution.
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| BIO C211 Biological Chemistry
3 0 3
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| Chemistry
and functions of constituents of cells and tissues;
introduction to enzymes; metabolism of carbohydrates,
lipids, aminoacids; nucleic acids and protein synthesis;
vitamins and hormones.
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| BIO C231 Biology Project Laboratory
3*
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| The
course includes projects involving laboratory
investigation or laboratory development in Biology. The
course is normally available to students of second or
higher level. The course must coterminate with a project
report.
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| BIO C241 Microbiology
2 3 3
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| Introduction
and classification of microbes; structure and physiology
of microbial cell; infection and immunity; host parasite
relationship; microbiology of milk, air, water
and food; physical and chemical methods of
controlling microbes; experiments
for isolation, cultivation, physiological and
biochemical characterization of microbes.
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| BIO C312 Developmental Biology
3 0 3
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| Scope and problems in developmental processes in
biology, role of different animal and plant models, cell
division and differentiation, cell interaction, genetic
control of morphogenesis in vertebrate and invertebrates,
tissue specific gene expression, organogenesis, germ cells
and fertilization, apoptosis, genomic imprinting, sex
determination, regeneration, teratology, post embryonic
development, aging and senescence. |
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| BIO C321 Cell Biology
3 0 3
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| Fundamental
processes of life at cellular and sub-cellular levels,
cell environments, membrane transport, cell movements,
division and control mechanisms.
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| BIO C322 Ecology
3 0 3
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| Ecosystem
productivity and trophism; environmental complex; limiting
factors; population and community; ecological regulation;
biogeographic regions; applied ecology.
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| BIO C331 Biophysics
3 0 3
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| A
study of molecules and their interaction forces;
bioenergetics and physical techniques as applied to
biological phenomena.
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| BIO C332 Genetics
3 0 3
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| Facts
and theories of heredity, their relation to the present
state of biological theory in general; elements of
population genetics; genetics and species concept.
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| BIO C342 General Physiology
3 0 3
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| Basic
functional processes in plants and animals; nutrition,
photosynthesis, circulation, respiration, excretion,
reproduction, hormonal mechanisms and irritability.
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| BIO C352 Cell
and Tissue Culture
Technology 3 0 3
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| Theories
and practices on in
vitro techniques for plants and animals, development of normal and tumor
cell lines, somatic hybridization, monoclonal antibody
production, hairy root cultures, secondary metabolite
production, scale-up strategies for large scale production
of biomass.
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| BIO C391 Instrumental Methods
of Analysis
4
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Principles,
configuration, applications of instruments
like mass spectrophotometer, NMR, UV, IR, X-ray
apparatus, atomic spectrophotometer, gas chromatography,
liquid scintillation
spectrophotometer,
laser device,
high voltage
electrophoresis, ultracentrifuge, DTA, TGA, etc.
The course is specially designed for students in
the first degree majoring in experimental sciences and
would require groups of students to work with the above
instruments in order to appreciate the potentiality of
such modern instrumental methods of
analysis. |
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| BIO C411 Laboratory
0 9 3
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Specially
designed for M.Sc.(Hons). Biological Sciences; cannot be
taken by others under any circumstances.
This
laboratory course is designed only for M.Sc.(Hons)
Biological Sciences students and aims to expose the
students to and build competence in selected techniques of
modern biology.
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| BIO C412
Introduction to
Bioinformatics
3 0 3
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| Introduction to genomics and proteomics, Human
genome and other sequencing projects; Biological database
and data mining; Similarity search and sequence alignment;
Protein structure prediction and structure analysis; Use
of software package in bioinformatics. |
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| BIO C413 Genetics
and Molecular Biology
3 0 3
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| Facts
and theories of genetics. Structure and function of
genetic material; DNA replication, repair and
recombination. Prokariotic and Eukaryotic transcription,
modification in RNA, translation, protein localization.
Molecular mapping of genome, genome sequencing, Oncogene
and tumor suppressor gene.
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| BIO C414 Genetic
Engineering
1 6 3
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| The primary objective of this course is to
familiarize the students with a comprehensive set of basic
techniques, which comprises of isolation of plasmid from
bacterial cell, preparation of competent cell,transformation
and various methods of gene transfer. restriction
digestion, restriction mapping, ligation, PCR, Southern
and Northern hybridization .Students will
be introduced to the dissection of mice and splenocyte culture.
An exposure will also be given on various plant
tissue culture techniques; micropropagation, callus and
suspension culture, isolation of DNA from plant cell and
its manipulation.
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| BIO C421 Enzymology
3 0 3 |
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Prerequisite
: BIO C211
Enzyme
nomenclature and classification; isolation and
purification; structures; kinetics; regulation of
enzymatic reactions; evaluation of enzymes and other
proteins.
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| BIO C431 Reproductive Physiology
3 0 3
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Prerequisite
: BIO C211
Study
of sexual cycles; biochemistry of fertilisation; control
of ovarian functions; gonadotropins; pheromones and
mammalian reproduction.
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| BIO C441 Biochemical Engineering
3 0 3
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| Principles of Chemical Engineering applied to
Bioprocesses; Kinetic Models for growth, substrate
utilization and product formation; Biological reaction
kinetics and applied enzyme catalysis; immobilized
biocatalysts; Bioreactor Design and Operation;
Fermentation, Upstream & Downstream processing; Novel
Bioreactor Configurations; Transport phenomena in
Bioprocesses; Instrumentation and control; Bioprocess
Optimization and Scale up; Industrial Protein Purification
Techniques; Commercial Enzymes & Biopharmaceuticals;
Bioprocess Patenting, Economics & Feasibility Studies. |
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| BIO C451 Bioprocess
Technology
3* |
| Bioprocess Principles; Kinetics of Biomass production,
substrate utilization and product formation; Kinetics of
enzyme catalyzed reactions and applied enzyme catalysis;
Fermentation process parameters and controls, Upstream
& Downstream processing; Bioreactor Design &
Operation; Transport processes in Bioreactors; Novel
Bioreactor Configurations; Immobilized biocatalysts;
Bioconversion; Protein Purification; Industrial
applications of Bioprocesses; Bioprocess Patenting &
Economics. |
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| BIO C461 Recombinant DNA
Technology
3 0 3
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| The course deals with theoretical aspects of
recombinant DNA manipulation.
Emphasis will be placed on procedures to create
chemeric molecules using examples from actual experimental
work. Vector designing, polymerase chain reaction, invitro
mutagenesis and cloning in prokaryotic and eukaryotic
vectors will be covered.
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| BIO C491 Special Projects
3
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| This
is an unstructured open-ended course where under the
overall supervision of an instructor-in-charge, batches of
students will be attached to different instructors. Each
batch will work on a specific time-bound project which is
of basic or peripheral
concern of his
discipline. Each student must submit a project report as a
culmination of his endeavour and investigation. The
instructor- in-charge will determine the choice of the
project and also whether or not the project report is to be
submitted jointly by a
group or
individually by a student. The course will aim to evaluate
student's actual ability to use the fundamentals of
knowledge and to meet new unknown situations as
demonstrated by the students' interaction
with the
instructors and
instructor-in- charge and aggregated in the project
report. The instructor-in- charge may assign specific
hours for formal brain-storming sessions.
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| BIO G511 Population and
Quantitative Genetics 5
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| Gene pool, allele frequency, genotype frequency,
Hardy-Weinberg equilibrium & its complications,
non-random breeding, genetic drift, genetic load, gene
flow, selection, intensity of selection pressure,
inbreeding & artificial selection, natural selection
& polymorphism, neutral theory & evolution
speciation. |
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| BIO G512 Molecular
Mechanism of Gene
Expression
Expression
3 2 5
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| Prokaryotic
and eukaryotic genomes and their topology: DNA - protein
interactions; RNA transcription and transcriptional
control; DNA replication; transcription in yeast; RNA
processing; translation; mechanism of gene expression in
pro and eukaryotes.
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| BIO G513 Microbial
and Fermentation Technology
5
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| Metabolic
Stoichiometry- energetics, fundamentals
of microbes and their morphology, Stoichiometry of cell
growth and product formation, fermentation kinetics,
phases of growth in batch culture, continuous culture and
fed-batch cultures, kinetics of cell growth, product
formation and substrate utilization-substrate and product
inhibition kinetics, enzyme technology. Industrial
Biotechnology- strain selection and improvement ,media
formulation and sterilization strategies, industrial
applications, fermentation and product recovery,
preparation of alcohols, antibiotics, organic acids,
enzymes, bakery and dairy products, biopharmaceuticals,
vaccine production. |
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| BIO G514 Molecular
Immunology 5
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| This
course will deal extensively with topics like molecular
basis of T and B cell antigen recognition and activation.
Immunity to microbes and diseases caused by humoral and
cell mediated immune responses will be covered and
emphasis placed on congenital and acquired
immunodeficiencies. Advanced topics like antibody
engineering will be discussed with the help of review
articles. |
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| BIO G522 Interferon Technology
2 2 4
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| Characterization, Functional activity, broad pleiotropic
agents, antiviral, anti-angiogenic, antitumor, anti-proliferative,
immunomodulatory effect, specific receptor binding,
mechanisms, sequencing, classification, Dosage formulation
Therapeutic study, side effects, molecular manipulation
and activity profile. |
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| BIO G532 Biostatistics and
Biomodelling
2 2 4
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| Probability
analysis variables in biology; standard deviation and
standard errors; correlation and correlation coefficient;
regression analysis; significance test; chi-square and
goodness of fit; applications of computers
in statistics; handling of
software on enzyme kinetics and protein sequence analysis;
computer analysis of nucleic acid structure |
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BIO
G541 Neural Network
Analysis
5
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| Basic concepts, Characteristics of nerve cells and neurons, Definition of
artificial neurons, Algorithms, network topology and
functions, Neural network application for learning, expert
systems, knowledge representation, speech recognitions and
synthesis, visual perception and pattern recognition and
language processing: Emphasis will be on a comparative
study with biological systems.
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| BIO G542 Advanced Cell and
Molecular Biology 5
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| Eukaryotic
cell cycle: restriction point, G1 phase progression, role
of cyclins, cancer cell cycles; growth factors and their
interaction with receptors: PDGF, EGF, VEGF, FGF, TGF;
stress responses: mechanisms molecular biology with
special reference to hypoxia; extracelular matrix and
adhesion molecules; cytokines: sources, molecular
structure, targets and mechanisms of
action; apoptosis, caspases and necrosis.
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| BIO G551 Membrane Biology
5
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| Concepts of biological membrane, Membrane constituents phospholipids,
glycolipids and cholesterol; Membrane bilayers,
amphipathic molecules, Self-assembly process; Membrane
proteins, lateral and transverse diffusion, fluid mosaic
model, Membrane permeability; Organization and dynamics of
membrane, Signal transduction, role of carbohydrate
components of membrane, Red-cell membrane proteins, Tools
and techniques in membrane study: electron microscope,
X-ray study, autoradiography and spectrometry. Immune
response, Surface properties, Kinetics of membrane-bound
processes.
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| BIO G611 Environmental
Biotechnology
3
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| Applications of biotechnology to the management of
environmental problems, role of biotechnology in
increasing plant and animal production through biological
insecticides, herbicide resistance, mineral cycling,
conservation of genetic resources and biological
nitrogen-fixation. Use of biotechnological processes in
pollution control, bioremediation of toxicants, treatment
of domestic and industrial waste will be emphasized.
Ethical issues related with the release of genetically
modified organisms would also be covered. |
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| BIO G612
Human Genetics
3 2 5
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| Epigenetic and Chromosomal Control of Gene Expression:
DNA methylation, Genomic imprinting and mammalian
development. DNA damage & repair:
Damage control during replication and mitosis, Genome
stability and checkpoint control, Disorders related to
aberrant DNA repair. Molecular genetics of
inherited disorders. Cancer
genetics: Genetic
analysis of various cancers, tumor
suppressor genes, metabolic polymorphisms and cancer
susceptibility. Genomics
& Proteomics: Human
genome project and
its applications in Gene
therapy, novel drug design approaches.
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| BIO G631 Membrane and
Liposome
Technology 2 2 4 |
| Membrane
structure and
biogenesis: techniques
for the study of membrane structure and properties; model
of membranes; molecular transport mechanisms; techniques
of artificial membrane productions; liposomes -
structure and
characteristics;
carrier mechanisms for targeting therapeutic
agents; industrial applications of liposomes.
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| BIO G632 Transgenic Technology
3 2 5
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| Transgenic
techniques as replacements of traditional breeding
practices; understanding faulty gene pool; development of
commercial and economically viable tissue
culture and their genetic improvement through r-DNA
strategies; development
of recombinant
transplants for improved genomic system.
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| BIO G641 Cell &
Tissue Culture Technology
2 2 4
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| Plant and animal cell culture from various organism;
types of cell lines; development and maintenance of cell
lines; tissue culture for viral growth, hybridization and
gene manipulation; hybridoma technology and protoplast
fusion. |
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| BIO G642 Experimental Techniques
5
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| Specially designed laboratory course which aims to
impart training in selected range of techniques such as,
salt fractionation, dialysis, PAGE with discontinuous
buffer solution, Western Blotting, Ion-exchange
chromatography and Gel filtration, Genomic DNA extraction
from Human Blood, bacteria, purification of DNA and
analysis, polymerase chain reaction, single, double and
partial restriction digestion, construction of genomic DNA
library, Southern Blotting, Karyotyping, short term
lymphocyte culture, RNA extraction and quantification. |
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| BIO G643 Plant Biotechnology
3 2 5
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| Commercially
important plant
parts and compounds; invitro living industries, plant
cell, protoplast and germ plasm culture, maintenance and
application; in vitro industrial production of secondary
metabolites, pharmaceutical products, enzymes
and food proteins; strategies for industrial production of
antibodies through crop farming.
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| BIO G651 Protein and Enzyme
Bioengineering 3 2 5
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| Sources,
isolation, purification and storage of protein
and/or enzymes; kinetics of enzyme catalyzed reactions;
biocatalyst reaction engineering; techniques of production
and recovery of enzymes; protein and enzyme modification;
clinical and
industrial applications of free and immobilized
enzymes.
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| BIO G661 Gene Toxicology
2 2 4
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| Origin
and fundamentals of Gene Toxicity; genotoxic effects in
plants and mammalian systems; screening and measurements
of genetoxicants; techniques in gene toxicology and their
application to human, agricultural and environmental
monitoring.
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| BIO G671 Bioconversion
Technology
3 2 5
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| Waste
and by-product utilization; down stream processing; biogas
production; principles of biodegradation process
parameters; bioreactor design and operation; exploitation
of waste streams enzyme-based bioconversions of high value
products.
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